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Every organ and tissue in the body contains a small number of what scientists call adult stem cells or progenitor cells.These cells have three characteristics in common: 1).The same is true for cancer: if you do not kill the cancer stem cells, the cancer is likely to return. Most cancers when caught early can be successfully treated.
These cells generally represent just 1% to 3% of all cells in a tumor, but they are the only cells with the ability to regenerate malignant cells and fuel the growth of the cancer. Embryonic stem cells are primitive cells that form inside an early embryo.
These cells also can be generated in a laboratory dish during a process called in-vitro fertilization.
Work is ongoing to identify stem cells in other tumor types.
Researchers take samples of tumors removed from patients during surgery, always with the patient's informed consent.
The Specialty Stem Cell Research covers all aspects of stem cell research ranging from molecular biology and cell biology to tissue regeneration and stem cells to translational research.
In addition, the Specialty will consider papers involving the fundamental aspects of stem cell research that are not covered by other areas of the field: cloning, pluripotency, reprogramming, proteomics, genetics, epigenetics, genomics, non-coding RNAs, and cancer stem cells.Adult stem cells can renew themselves through cell division for long periods of time. Adult stem cells retain the ability to give rise to several (but not all) types of cells in the body. Different types of adult stem cells give rise to different specialized cells.Pancreatic stem cells, for example, are the ancestors of insulin-producing islet cells in the pancreas.Treatments that target only cancer stem cells would cause fewer side effects for patients.Cancer stem cells were first identified in leukemia.When only specific sorted cells form new tumors, researchers then test those cells for properties of stem cells.The next step is to understand how cancer stem cells work and identify drugs that will kill the stem cells without harming normal cells.Four to five days after a human egg is fertilized by sperm, the dividing mass of cells is called a blastocyst.Scientists can remove the inner cell mass from the blastocyst and grow stem cells in a culture dish in the laboratory.Hematopoietic stem cells develop into all the different types of cells in the human blood and immune systems.Cancer stem cells are a type of adult or progenitor cell found in most types of cancer.